Monodisperse PEG linkers are PEG polymers with a single molecular weight of less than 1000. It lacks the polydispersity of traditional polydisperse PEG polymers. Monodisperse PEG can be used in various pharmaceutical applications, including medical research, drug-release, nanotechnology, ADC development and cell culture, etc. Studies have found that inserting monodisperse PEG into small molecule drugs can increase the water solubility and molecular weight of the drug, thereby increasing circulation time of the drug in the body and reducing the effects of steric hindrance and binding when the polymer is modified by high molecular PEG.

Huateng Pharma provides monodisperse PEGs with various functional groups and reactive groups at the end of the chain, in both non-GMP and GMP grade. Linear monodisperse PEG linkers with molecular weights
and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at sales@huatengusa.com about pricing and availability.